◀ Back to MMP14
MMP14 — MMP16
Text-mined interactions from Literome
Ellerbroek et al., Cancer Res 1999
(Ovarian Neoplasms) :
Aggregation of beta1 integrins with immobilized 21C8 or P4C10 antibodies stimulated
MMP dependent pro-MMP-2 activation and accumulation of a M ( r ) 43,000 form of membrane type 1 MMP
(MT1-MMP) , a cell surface activator of pro-MMP-2, in cell extracts
Majka et al., Invest Ophthalmol Vis Sci 2001
(Disease Models, Animal...) :
During the angiogenic period from P13 to P17,
MMP-2 and -9, and
MT1-MMP message expression
increased in experimental retinas compared with control samples
Shofuda et al., FASEB J 2001
:
Furthermore, when
MT3-MMP and MT1-MMP were coexpressed,
MT1-MMP degradation was
enhanced ; this result supports the possibility that MT3-MMP can degrade MT1-MMP
Ruangpanit et al., Exp Cell Res 2002
:
Accumulation of collagen over time correlated with increased levels of both mature MMP-2 and cell associated membrane type 1-MMP
(MT1-MMP) , and subsequently
increased mRNA levels for
MT1-MMP , providing temporal resolution of the `` nontranscriptional '' and `` transcriptional '' effects of collagen on MT-1MMP functionality
Munshi et al., J Biol Chem 2004
(Carcinoma, Squamous Cell...) :
Treatment of oral squamous cell carcinoma cells with TGF-beta1 promoted
MMP dependent cell scattering and collagen invasion, increased expression of MMP-2 and
MT1-MMP , and enhanced MMP-2 activation
Sanka et al., Invest Ophthalmol Vis Sci 2007
:
Primary human TM ( HTM ) cells treated with different actin cytoskeleton interfering agents, including cytochalasin D, latrunculin A, ethacrynic acid ( ECA ), a Rho kinase inhibitor ( Y-27632 ), and H-7 ( serine/threonine kinase inhibitor ), were examined for changes in actin cytoskeletal organization by phalloidin staining,
MMP-2 activation by gelatin zymography, expression of
MT1-MMP by quantitative real-time PCR analysis, levels of tissue inhibitor of metalloproteinases ( TIMP-1 and TIMP-2 ), and activation of p38 mitogen activated protein kinase ( p38 MAPK ) and extracellular signal regulated protein kinase ( ERK ) by immunoblotting
Ito et al., Biochem Biophys Res Commun 2010
(Disease Progression...) :
In HT1080 cells, positive both in MT1-MMP and
MT2-MMP , the migration as well as the invasion was
impaired by
MT1-MMP or MT2-MMP suppression
Swamydas et al., Cell Adh Migr 2013
(Mammary Neoplasms, Animal...) :
Additionally, the addition of specific MMP9/MMP13 and
MMP14 inhibitors
prevented the
MMP activities of supernatants collected from 4T1 cells incubated with D1CM, CCL5 or CCL9