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ATR — CHEK2

Pathways - manually collected, often from reviews:

• KEGG Cell cycle: ATM/ATR → CHEK1/CHEK2 (protein-protein, phosphorylation)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: ATR — CHEK2 (direct interaction, enzymatic study) Olson et al., J Biol Chem 2006*
• IRef Biogrid Interaction: ATR — CHEK2 (direct interaction, enzymatic study) Matsuoka et al., Proc Natl Acad Sci U S A 2000*
• IRef Hprd Interaction: ATR — CHEK2 (in vivo) Matsuoka et al., Proc Natl Acad Sci U S A 2000*, Tanaka et al., Nat Cell Biol 2001*, Xu et al., Mol Cell Biol 2002*, Tsvetkov et al., J Biol Chem 2003*, Martinho et al., EMBO J 1998*
• IRef Hprd Interaction: ATR — CHEK2 (in vitro) Matsuoka et al., Proc Natl Acad Sci U S A 2000*, Tanaka et al., Nat Cell Biol 2001*, Xu et al., Mol Cell Biol 2002*, Tsvetkov et al., J Biol Chem 2003*, Martinho et al., EMBO J 1998*
• STRING interaction: ATR — CHEK2 (interaction, mapped from reactome mint intact)
• STRING interaction: CHEK2 — ATR (interaction, mapped from kegg_pathways)