Porter et al., J Biol Chem 2000
:
Reciprocal regulation of Hck activity by phosphorylation of Tyr ( 527 ) and Tyr ( 416 ) ... Phosphorylation of Tyr ( 416 ) is required for Hck activation
Warmuth et al., J Biol Chem 1997
:
Finally, experiments with a series of kinase negative Bcr-Abl mutants showed that Hck phosphorylated Bcr-Abl and induced the binding of Grb2 to Tyr177 of Bcr-Abl