Koshimizu et al., Mol Endocrinol 2011
:
Furthermore, a luciferase reporter assay demonstrated serpinin induced up-regulation of PN-1 promoter activity in an Sp1 dependent manner
Guttridge et al., J Neurochem 1996
:
Characterization of the human protease nexin-1 promoter and its regulation by Sp1 through a G/C-rich activation domain ... Cotransfection experiments into the Sp1-deficient Drosophila SL2 cell line also showed that Sp1 activates PN-1 promoter activity in a dose dependent fashion