Gene interactions and pathways from curated databases and text-mining

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GH1 — STAT1

Pathways - manually collected, often from reviews:

  • Reactome Reaction: GH1 → STAT1 (indirect_complex)
  • Reactome Reaction: GH1 → STAT1 (reaction)

Text-mined interactions from Literome

Boutinaud et al., Domest Anim Endocrinol 2004 : Growth hormone increases Stat5 and Stat1 expression in lactating goat mammary gland : a specific effect compared to milking frequency
Takeda et al., J Endocrinol 1997 : Because human growth hormone ( hGH ) activates Stat1 , 3, 5 and human prolactin ( hPRL ) activates Stat5, these results show that hPL uses a unique signal transduction pathway which is different from hGH and hPRL