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CIITA — IL10

Text-mined interactions from Literome

O'Keefe et al., Eur J Immunol 1999 : TGF-beta1, IL-4, and IL-10 inhibition of IFN-gamma induced CIITA mRNA accumulation was not due to destabilization of CIITA mRNA, suggesting an effect at the level of transcription ... In primary murine microglia, IL-10 and TGF-beta1 inhibited IFN-gamma induced CIITA and class II MHC expression
Yee et al., J Immunol 2005 : In addition, reintroducing CIITA into CIITA ( -/- ) DC reduced production of IL-10 ... In all, these data suggest that CIITA negatively regulates expression of IL-10 , and that CIITA may direct DC function in ways that extend beyond control of MHC class II