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CD40 — LEP

Text-mined interactions from Literome

Gultekin et al., World J Gastroenterol 2007 (Acute Disease...) : Exogenous leptin attenuates inflamma-tory changes, and reduces pro-inflammatory cytokines, nitric oxide levels, and CD40 expression in cerulein induced AP and may be protective in AP associated ALI
Lam et al., J Biol Chem 2007 : Leptin induces CD40 expression through the activation of Akt in murine dendritic cells ... In this study, we showed that leptin induced CD40 expression in murine DC and significantly up-regulated their immunostimulatory function in driving T cell proliferation ... Thus, our results have elucidated the molecular mechanisms underlying leptin induced CD40 expression and DC maturation