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ICAM1 — TAT
Text-mined interactions from Literome
Myou et al., J Immunol 2002
:
Neither
TAT-dnRas nor PD98059
blocked eosinophil adhesion to
ICAM-1 , up-regulation of CBRM1/5, or focal surface clustering of Mac-1 caused by PMA
Song et al., Exp Mol Med 2007
:
Inhibition of Tat induced ROS generation by N-acetyl cysteine, vitamin C and diphenyl iodonium suppressed
Tat induced NF-kappaB activation,
ICAM-1 and VCAM-1 expression, and monocyte adhesion in CRT-MG
Song et al., Free Radic Biol Med 2011
(AIDS Dementia Complex) :
Nox2 based NADPH oxidase mediates HIV-1
Tat induced
up-regulation of
VCAM-1/ICAM-1 and subsequent monocyte adhesion in human astrocytes ... HIV-1
Tat induced
up-regulation of
VCAM-1/ICAM-1 and subsequent increased adhesion of monocytes to astrocytes were blocked by a general NADPH oxidase inhibitor, diphenylene iodonium, and a specific inhibitor of NADPH oxidase assembly, 9R3A-gp91ds
Duan et al., PloS one 2013
(Cardiomyopathies) :
Furthermore,
Tat stimulated regulation of
ICAM-1 via miR-221/-222 involved the NF-kB dependent pathway ... Taken together, these findings implicate that
Tat mediated induction of
ICAM-1 expression plays a critical role in monocyte adhesion observed in HIV-1 associated cardiomyopathies
Kelly et al., AIDS 1998
(AIDS-Related Opportunistic Infections...) :
Tat induced the expression of the adhesion molecules vascular cell adhesion molecule 1 ( VCAM-1 ) and
intercellular adhesion molecule 1 ( ICAM-1 ) and the cytokines monocyte chemoattractant protein 1 ( MCP-1 ) and interleukin 6 (IL-6)