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CYP19A1 — TGFB1

Text-mined interactions from Literome

Richards et al., J Steroid Biochem Mol Biol 2002 (Breast Neoplasms) : The effects of epidermal growth factor (EGF), transforming growth factor-beta ( TGFbeta ), and tetradecanoyl phorbol acetate ( TPA ) on aromatase and COXs were studied in primary cultures of normal human adipose stromal cells and in cell cultures of normal immortalized human breast epithelial cells MCF-10F, estrogen-responsive human breast cancer cells MCF-7, and estrogen-unresponsive human breast cancer cells MDA-MB-231
Bourguiba et al., Biol Reprod 2003 : Conversely, transforming growth factor (TGF) beta1 inhibited Cyp19 gene expression in a dose- and a time dependent manner in both PS and RS
Bourguiba et al., J Steroid Biochem Mol Biol 2003 : In the present study we have analyzed the putative effects of steroid hormones, transforming growth factor beta ( TGFbeta ), cytokine ( tumor necrosis factor alpha, TNFalpha ) and dexamethasone ( Dex ) on CYP19 expression in these purified testicular cells from adult rat
Carreau et al., Reprod Biol 2004 : Moreover, we have demonstrated that in highly purified germ cells from adult rats ( pachytene spermatocytes and round spermatids ), transforming growth factor beta ( TGFbeta ) inhibited the expression of Cyp19 in both germ cell types
Emoto et al., Proc Soc Exp Biol Med 1991 : Although basic fibroblast growth factor ( 1-100 ng/ml ), acidic fibroblast growth factor ( 1 ng/ml ), epidermal growth factor ( 1 ng/ml ), platelet derived growth factor ( 1 ng/ml ), tumor necrosis factor ( 1 ng/ml ), and transforming growth factor-beta 1 ( 1 ng/ml ) have no effect on basal aromatase activity in human skin fibroblasts, all of these growth factors inhibited the ability of dibutyryladenosine 3',5'-cyclic monophosphate to stimulate aromatase activity
Zhou et al., Reproductive biology and endocrinology : RB&E 2009 : The objective of this study was to investigate the molecular mechanisms underlying the regulatory effect of TGF-beta1 on aromatase expression ... The transcriptional regulation of aromatase gene by TGF-beta1 is mediated by the canonical TGF-beta pathway involving TbetaRII, ALK5 and Smad2