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E2F3 — TGFB1
Text-mined interactions from Literome
Fan et al., J Cell Sci 2002
:
In this study, we examined the downstream effects of
TGF-beta1 induced apoptosis and the potential roles for pRb and
E2F
Herzinger et al., Oncogene 1995
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We have studied the
effect of
TGF-beta 1 on protein binding to a transcription factor
E2F consensus element in extracts from early passage human keratinocytes ( HFKs ) and a permanent human keratinocyte cell line ( HaCaT )
Bang et al., J Biol Chem 1996
:
TGF-beta1 increased the binding of p107 to the transcription factor
E2F , leading to decreased c-Myc protein levels
Birchenall-Roberts et al., Oncogene 1996
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Surprisingly, in 32D-abl cells,
TGF-beta1 , a potent G1/S inhibitor of 32D-123 and 32D-abl cell growth,
increased E2F transactivation as shown by increased c-myc promoter-CAT and GAL4-E2F-1 activity