UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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CASP8 — ITGAV

Pathways - manually collected, often from reviews:

NCI Pathway Database Integrins in angiogenesis: alphav/beta3 Integrin complex (ITGAV-ITGB3) → Caspase 8 (CASP8) (modification, collaborate) Stupack et al., J Cell Biol 2001
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database Integrins in angiogenesis: Caspase 8 (CASP8) → alphav/beta3 Integrin/Caspase 8 complex (ITGAV) (modification, collaborate)
Stupack et al., J Cell Biol 2001
Evidence: mutant phenotype, assay, physical interaction