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IL4 — MOCOS

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Mellor et al., Proc Natl Acad Sci U S A 2003 : We now report that hMCs express the type 2 receptor for cysLTs ( CysLT2R ) as well, and that the amount of surface CysLT2R protein increases in response to priming with IL-4
Okayama et al., Eur Respir J 2009 (Asthma) : Stimulation of MCs with interleukin (IL)-4 alone did not affect the TSLP mRNA expression, while pre-incubation of MCs with IL-4 for 48 h significantly enhanced the FcepsilonRI mediated TSLP mRNA expression ( by 53.7+/-15.9-fold ; p < 0.05 ) and the amount of TSLP in the cell pellets increased significantly from 23.4+/-4.3 pg mL(-1) to 121.5+/-3.7 pg mL(-1) ( p < 0.0001 )