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ESR1 — MYLIP
Text-mined interactions from Literome
Adams et al., Mol Endocrinol 2007
(Breast Neoplasms) :
This study examined whether
miR-206 , previously shown to be elevated in estrogen receptor (ER)alpha negative breast cancer,
regulates the expression of
ERalpha ... Overexpression of
pre-miR-206 reduced
ERalpha and beta-actin protein levels, with no effect on ERbeta, E-cadherin, or glyceraldehyde-3-phosphate dehydrogenase
Zhao et al., J Biol Chem 2008
(Breast Neoplasms) :
Ectopic expression of
miR-221 and miR-222 in MCF-7 and T47D cells
resulted in a decrease in expression of
ERalpha protein but not mRNA, whereas knockdown of miR-221 and miR-222 partially restored ERalpha in ERalpha protein-negative/mRNA positive cells
Tchatchou et al., Carcinogenesis 2009
(Breast Neoplasms) :
According to in silico analysis,
ESR1_rs2747648 affects the binding capacity of
miR-453 , which is stronger when the C allele is present
Pandey et al., Mol Cell Biol 2009
(Breast Neoplasms) :
miR-22 overexpression
leads to a reduction of
ER alpha levels, at least in part by inducing mRNA degradation, and compromises estrogen signaling, as exemplified by its inhibitory impact on the ER alpha dependent proliferation of breast cancer cells
Chen et al., Mol Ther 2011
(Carcinoma, Hepatocellular...) :
The purpose of this study was to investigate whether miR-26a, regulated by a human a-fetoprotein ( hAFP ) and human telomerase reverse transcriptase ( hTERT ) dual promoter, could be specifically expressed in liver tumor cells to suppress their growth and to clarify whether
estrogen receptor-a ( ERa ) is
regulated by
miR-26a and involved in the HCC process
Zhao et al., Arterioscler Thromb Vasc Biol 2013
:
In cultured vascular smooth muscle cells ( VSMC ), E2-mediated upregulation of
miR-203 is
mediated by
estrogen receptor-a ( but not estrogen receptor-ß ) via transcriptional upregulation of the primary miR