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CD28 — IL3

Text-mined interactions from Literome

Okkenhaug et al., Nat Immunol 2001 : Nonetheless, this mutated form of CD28 still prevents the induction of anergy and promotes T cell proliferation, interleukin 2 secretion and B cell help
Fraser et al., Mol Cell Biol 1992 (Leukemia, T-Cell) : Stimulation of CD28 in the presence of TCR-like signals increases the activity of the GM-CSF, IL-3 , and IFN-gamma promoters by three- to sixfold
Abreu et al., Arthritis Res Ther 2010 (Arthritis, Experimental...) : Ex vivo, Rac1 inhibitory peptide suppressed T-cell receptor/CD28 dependent production of tumor necrosis factor alpha, interferon gamma and interleukin-17 by T cells from collagen primed mice, and reduced induction of ICOS and CD154, T-cell costimulatory proteins important for B-cell help
Dumont et al., J Immunol 1998 : FK506 also reduced CD3/CD28 induced production of IL-3 , IL-4, IL-10, TNF-alpha, and IL-6 but augmented that of GM-CSF, IL-5, IFN-gamma, and IL-13