Gene interactions and pathways from curated databases and text-mining

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COX4I2 — HIF1A

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: COX4I2 → HIF1A (increases)
    Evidence: In this regard, HIF1 also reduces levels of ROS by optimizing respiration efficiency through inducing cytochrome c oxidase subunit IV, isoform 2 (COX4I2) to replace the less efficient nonhypoxic COX4I1 (REF. 35).