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NOS2 — PTGS1

Text-mined interactions from Literome

West et al., Crit Care Med 2008 : Selective COX-1 inhibition with SC560 similarly increased gastric iNOS expression and exacerbated gastric injury, while the selective COX-2 inhibitor NS398 had no effect on iNOS expression or gastric injury in the presence of lipopolysaccharide
Matsui et al., Anesth Analg 2010 : Our findings suggest that ( a ) activation of spinal microglia via TLR4 but not NK1 receptors produces PGE ( 2 ) and NO release from these cells ; ( b ) the evoked PGE ( 2 ) release is generated by both COX-1 and COX-2, and ( c ) the COX-PGE ( 2 ) pathway is regulated by p38 and NOS2