Gene interactions and pathways from curated databases and text-mining

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NOX1 — STAT1

Text-mined interactions from Literome

Kuwano et al., Am J Physiol Cell Physiol 2006 (Inflammation) : A Janus protein tyrosine kinase 2 inhibitor ( AG490 ) blocked the IFN-gamma stimulated tyrosine phosphorylation of STAT1, promoter activity of the -4,831 to +195 bp region, Nox1 mRNA expression, and O ( 2 ) ( - ) production, also suggesting a crucial role of STAT1 and GAS in the IFN-gamma stimulated transcription of the Nox1 gene
Yang et al., J Immunol 2013 (Inflammation) : TLR3 induced ROS generation, NOX2 , and p47(phox) were required for the phosphorylation and nuclear translocation of STAT1 and STAT2