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STS — TP53

Text-mined interactions from Literome

Ohtsuka et al., Nat Cell Biol 2004 : We also show that induction of ASC after exposure to genotoxic stress is dependent on p53
Parsons et al., Oncogene 2006 (Cell Transformation, Neoplastic) : Although previous work has suggested that TMS1/ASC may be directly regulated by p53 , we found that whereas treatment of breast epithelial cells or normal diploid fibroblasts with DNA damaging agents resulted in the stabilization of endogenous p53 and a concomitant increase in p21, it had little impact on the expression of TMS1/ASC mRNA or protein
Geng et al., J Neuropathol Exp Neurol 2007 : We found that both STS- and genotoxin induced cerebellar NPC death were markedly inhibited by p53 or Bax deficiency
Geng et al., J Histochem Cytochem 2010 : We found that STS rapidly increased p53 cytoplasmic immunoreactivity in neuritic-like processes in C17.2 cells, which preceded Bax activation and caspase-3 cleavage
Sugimoto et al., Mol Med Report 2009 : UVB induced p53 expression was notably suppressed by Asc2P or dehydro-Asc, but not by Asc ... In contrast, mutation-type p53 ( mt-p53 ), which is known to interfere with wt-p53 function, was not markedly expressed in the nuclei and was explicitly suppressed by Asc2P but not by Asc, dehydro-Asc or Asc2G, which was not cytoprotective against UVB
Song et al., Prog Neuropsychopharmacol Biol Psychiatry 2012 : STS increased the expression of p53 and decreased that of Bcl-2 ... These effects of STS on p53 and Bcl-2 are restored by all of Li, VPA, CBZ and LTG
Drexler et al., Proc Natl Acad Sci U S A 2012 (Cell Transformation, Neoplastic...) : Stimulation of primary mouse keratinocytes or the human keratinocyte cell line HaCaT with UVB induced an ASC dependent phosphorylation of p53 and expression of p53 target genes