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IL6 — IRF2

Text-mined interactions from Literome

Mudter et al., Inflamm Bowel Dis 2011 (Colitis...) : In contrast to DSS colitis, IRF4 deficiency was protective in T-cell dependent transfer colitis associated with reduced RORa/?t levels and impaired IL-6 , IL-17a, and IL-22 production, suggesting that IRF4 acts as a master regulator of mucosal Th17 cell differentiation
Harroch et al., J Biol Chem 1993 : The dissociation between induction of mRNAs and of protein binding observed suggests that the activity of the IRF proteins is regulated by IL-6