Gene interactions and pathways from curated databases and text-mining

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COL1A1 — MMP2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Théret et al., Hepatology 1999 : Collagen I induced a dose dependent MMP2 activation, which was not blocked by both actinomycin and cycloheximide
Guo et al., J Biol Chem 2003 : Type I collagen induced MMP-2 activation coincides with up-regulation of membrane type 1-matrix metalloproteinase and TIMP-2 in cardiac fibroblasts
Kim et al., J Biochem Mol Biol 2007 : Type I collagen induced pro-MMP-2 activation is differentially regulated by H-Ras and N-Ras in human breast epithelial cells ... Type I collagen induced activation of pro-MMP-2 only in H-Ras MCF10A cells but not in N-Ras MCF10A cells
Azzam et al., J Natl Cancer Inst 1993 (Breast Neoplasms...) : Collagen I-induced MMP-2 activation is restricted to highly invasive estrogen receptor negative, vimentin positive human breast cancer cell lines, is independent of MMP-2 production, and is associated with metastatic potential