Gene interactions and pathways from curated databases and text-mining

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CRK — MMP2

Text-mined interactions from Literome

Li et al., J Huazhong Univ Sci Technolog Med Sci 2011 (Lung Injury) : It was suggested that RA had a protective effect on hyperoxia induced lung injury by down regulating the expression of MMP-2 through decreasing the JNK and p38 activation in hyperoxia
Deraz et al., PloS one 2011 (Carcinoma, Squamous Cell...) : Interestingly, MMP-10 overexpression induced the decreased p38 activity and MMP-10 knockdown induced the increased p38 activity
Heijink et al., Thorax 2013 (Pulmonary Disease, Chronic Obstructive) : Exogenously added WNT-4 significantly increased CXCL8/IL-8, IL-6, CCL5/RANTES, CCL2/MCP-1 and vascular endothelial growth factor ( VEGF ) secretion in 16HBE, but did not affect the canonical WNT target genes MMP-2 , MMP-9, fibronectin, ß-catenin, Dickkopf and axin-2, and induced activation of the non-canonical signalling molecule p38