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ANXA2 — IFNG

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: Complex of ANXA2-MAP3K4 → IFNG (increases) Halfter et al., Biochem J 2005*
  Evidence: Furthermore, the calcium-binding protein, annexin II, and the calcium-regulated kinase, Pyk2, co-immunoprecipitate with MEKK4 after treatment with IFNgamma.

Text-mined interactions from Literome

Hastie et al., J Biol Chem 2008 (Neoplasm Invasiveness...) : Interferon-gamma reduces cell surface expression of annexin 2 and suppresses the invasive capacity of prostate cancer cells ... Surface expression of annexin 2 was reduced in cells treated with glyburide, an ABCA1 inhibitor, whereas inhibition of calpain abrogated IFNgamma induced annexin 2 down-regulation and suppression of Matrigel invasion
Gao et al., Zhonghua Nan Ke Xue 2008 (Neoplasm Invasiveness...) : IFN-gamma significantly inhibited the expression of annexin-2 in prostate cancer cell lines LNCaP and PC-3 ( P < 0.05 )