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CCR6 — IFNG
Pathways - manually collected, often from reviews:
-
OpenBEL Selventa BEL large corpus:
CCR6
→
IFNG
(increases)
Evidence: CCR6 is expressed by airway epithelial cells in response to IFNG.
Text-mined interactions from Literome
Dieu-Nosjean et al., J Immunol 2001
:
IL-10
induces CCR6 expression during Langerhans cell development while IL-4 and
IFN-gamma suppress it ... In contrast,
IFN-gamma induced
CCR6 loss was irreversible and was concomitant to the induction of DC maturation
Facco et al., J Leukoc Biol 2007
(Acute Disease...) :
In vitro kinetic studies demonstrated that
CCR6 is
induced rapidly by IL-2, IL-18, and
IFN-gamma
Rivino et al., J Exp Med 2010
:
However, optimal TCR stimulation of
CCR6 ( + ) T cells
induced expression of IL-2,
interferon-gamma , CCL20, and CD40L, and autoreactive CCR6 ( + ) T cell lines responded to various recall antigens
Zella et al., Blood 1998
:
Interferon-gamma increases expression of chemokine receptors CCR1,
CCR3 , and CCR5, but not CXCR4 in monocytoid U937 cells