Mason et al., J Immunol 2002
(Inflammation...) :
Recent studies have shown that c-Rel , a member of the NF-kappaB family of transcription factors, is essential for LPS induced IL-12p40 production by macrophages
Tomczak et al., J Immunol 2006
(MAP Kinase Signaling System) :
Inhibition of the induction of IL-12 p40 by ERK was independent of c-Rel , a known positive regulator of IL-12 p40 Kumar et al., Proc Natl Acad Sci U S A 1993
:
Competition assays with a Rel derived peptide comprising the DNA binding region specifically alleviated p40 mediated inhibition of v-Rel DNA binding activity, whereas a covalently modified Rel peptide was inactive