Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
GATA2
→
IGF1R
(increases, IGF1R Activity, GATA2 Activity)
Musarò et al., Nature 1999* Evidence: IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1. Thus, IGF-1 induces calcineurin-mediated signalling and activation of GATA-2, a marker of skeletal muscle hypertrophy, which cooperates with selected NF-ATc isoforms to activate gene expression programs.