Osses et al., Am J Physiol Cell Physiol 2002
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These results suggested that the expression of myogenin is not sufficient to successfully drive skeletal muscle formation and that ECM is required to complete the skeletal muscle differentiation process
Melo et al., J Cell Biochem 1996
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These results suggest that the expression of myogenin is independent of the presence of ECM , but that the presence of ECM is essential for the formation of myotubes and the expression of later muscle-specific gene products