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EDN1 — PKD1

Text-mined interactions from Literome

Cuello et al., Circ Res 2007 : In myocytes transduced to express wild-type PKD, the heterologously expressed enzyme was activated by endothelin 1 (ET1) ( 5 nmol/L ), as reflected by PKD phosphorylation at Ser744/Ser748 ( PKC phosphorylation sites ) and Ser916 ( autophosphorylation site )
Guo et al., J Biol Chem 2011 (Heart Failure) : The a ( 1 ) -adrenergic receptor agonist norepinephrine selectively activates PKD1 , thrombin and PDGF selectively activate PKD2, and endothelin-1 and PMA activate both PKD1 and PKD2 ... Endothelin-1 activates PKD via both rapid PKC dependent and more sustained PKC independent mechanisms