◀ Back to IL5

CD4 — IL5

Text-mined interactions from Literome

Richards et al., Eur J Immunol 2000 : Glucocorticoids are highly effective in the treatment of allergy and asthma and inhibit the synthesis of IL-4, IL-5 and IL-13 by disease promoting CD4 ( + ) Th2 cells
Matsumoto et al., Int Arch Allergy Immunol 2003 (Eosinophilia...) : We examined the role of IL-5 in CD4+ T cell activation, cytokine production, and AHR upon Asc sensitization
Soldan et al., J Immunol 2003 (Multiple Sclerosis, Chronic Progressive...) : The increase in IL-5 was primarily due to an increase in CD4 ( + ) and CD8 ( + ) T cells, the increase in IL-10 was primarily due to an increase in CD64 ( + ) monocytes/macrophages with some effect in T cells, while the decrease in TNF-alpha was primarily due to a decrease in CD8 ( + ) T cells
Chihara et al., Eur Cytokine Netw 1992 : Induction of CD23, CD25 and CD4 expression on an eosinophilic cell line ( EoL-3 ) by interleukin-3 (IL-3), granulocyte-macrophage colony stimulating factor ( GM-CSF ) and interleukin-5 (IL-5) ... The effects of IL-3, GM-CSF and IL-5 on the expression of CD23 ( Fc epsilon RII ), CD25 ( IL-2R/p55 ) and CD4 on an eosinophilic cell line ( EoL-3 ) were investigated by flow cytometry
Pepe et al., Curr Pharm Des 2006 : This Th1 polarizing activity is mediated by interleukin-12 released by infected CDs in the presence of CD4 ( + ) cells
Wells et al., J Allergy Clin Immunol 2007 (Inflammation...) : Adoptive transfer of transgenic antigen-specific CD8, but not CD4 , cells resulted in increased IL-12 levels and reduced IL-13 and IL-5 levels in bronchoalveolar lavage fluid, coupled with substantially reduced airway eosinophilia after repeated allergen inhalation, a process mimicked by intranasal administration of IL-12 and inhibited by anti-IL-12 antibody
Ariga et al., Immunology 2007 : Using T-cell receptor ( TCR ) transgenic mice, we demonstrate that TCR stimulation of naive CD4 ( + ) T cells induces transient T-bet expression, interleukin (IL)-12 receptor beta2 up-regulation, and GATA-3 down-regulation, which leads to T helper ( Th ) 1 differentiation even when the cells are stimulated with peptide loaded I-A ( b ) -transfected Chinese hamster ovary cells in the absence of interferon-gamma (IFN-gamma) and IL-12
Leech et al., J Immunol 2007 (Asthma...) : Most convincingly, transfer of CD4 ( + ) CD25 ( + ) Foxp3 ( + ) T cells from Ag naive mice ( natural Tregs ) abolished AAI, decreased dMLN IL-5 and IL-13 secretion, increased dMLN IL-10 secretion, abolished IgE, and decreased IgG1 Abs. Blocking IL-10 receptor function in vivo did not block the anti-inflammatory function of transferred natural Tregs but did restore dMLN IL-5 and IL-13 secretion
Verma et al., Blood 2009 : CD4 ( + ) CD25 ( + ) T cells from tolerant hosts given IL-2 cultured cells had increased Il-5 and Ifngammar mRNA
Reyes et al., Am J Transplant 2013 (Conjunctivitis, Allergic...) : Exogenous IL-4, but not IL-5 or IL-13, prevented Treg suppression of CD4 ( + ) effector T cells isolated from naïve mice
Vandergeeten et al., Blood 2013 (HIV Infections) : When administered to HIV infected subjects receiving suppressive ART, interleukin-7 (IL-7) increases the number of CD4 ( + ) T cells by promoting their survival and proliferation
Takamoto et al., Immunology 1995 (Toxocariasis) : Production of IL-5 was reduced by in vivo depletion of CD4+ cells only and both CD4+ and CD8+ T cells, by intraperitoneal injection with appropriate mAb ; IL-5 production was stimulated by anti-CD3 mAb
Chihara et al., Nihon rinsho. Japanese journal of clinical medicine 1993 : The effects of IL-3, GM-CSF and IL-5 on the expression of CD23 ( Fc ( E ) RII ), CD25 ( IL-2R/p55 ) and CD4 on an eosinophilic cell line ( EoL-3 ) were investigated by flow cytometry
Simeonovic et al., J Immunol 1997 (Neovascularization, Pathologic) : We previously identified CD4 T cell dependent enhancement of intragraft IL-3, IL-4, and IL-5 mRNA expression during acute xeno-rejection in CBA/H recipient mice
Suzuki et al., J Virol 1999 : Among them, interleukin-12 (IL-12) and IL-4 induce naive CD4 ( + ) T cells to become T-helper 1 ( Th1 ) or Th2 cells, respectively