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Text-mined interactions from Literome

Hermoso et al., Pflugers Arch 2001 : In the range of concentrations similar to that produced by preimplantation embryos, PAF increased the CBF in a dose dependent manner ... To demonstrate this hypothesis, cyclooxygenase-2 (COX-2) was selectively blocked by a specific inhibitor, NS-398, and the PAF induced CBF increase was abolished ... Moreover, a phospholipase A2 (PLA2) inhibitor, AACOCF3, blocks the PAF induced CBF increase
Mehta et al., Prostaglandins Leukot Med 1986 : PAF produced an initial increase followed by a decrease in coronary blood flow (CBF) ... These effects of PAF on CBF were dose dependent, and associated with an increase in prostacyclin and thromboxane A2 metabolites
Ganbo et al., Arzneimittelforschung 1995 : These findings indicated that ibudilast activates CBF and inhibits the effect of PAF and LTD4 on ciliated cells, and consequently improves the pathogenesis of allergic disorders such as the inhibited mucociliary transport system and airway hyperresponsiveness