◀ Back to KSR1
KSR1 — TNF
Text-mined interactions from Literome
Yan et al., Cancer Res 2001
(MAP Kinase Signaling System) :
Furthermore,
TNF-alpha induced Raf-1 threonine phosphorylation, kinase activity toward MEK1, and association with
KSR are also inhibited by kiKSR expression ... Our data also show by sequential in vitro kinase assays that
TNF-alpha enhances
KSR phosphorylation of Raf-1 on threonine, enhancing Raf-1 kinase activity toward MAP kinase kinase
Yan et al., Cancer Res 2001
(MAP Kinase Signaling System) :
Our laboratory reported that
kinase suppressor of Ras (KSR) regulates
TNF activation of the Raf/mitogen activated protein ( MAP ) kinase/extracellular signal regulated kinase ( ERK ) kinase/ERK signaling cassette by threonine phosphorylation of Raf-1, regulating proliferation and differentiation pathways ... However,
TNF activation of p38 or stress activated protein kinase/c-Jun NH ( 2 ) -terminal kinase is not
inhibited by disruption of
KSR signaling