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MYLIP — SP1
Text-mined interactions from Literome
Ogawa et al., Biochem Biophys Res Commun 2010
:
miR-29b also
had an effect on
SP1 expression
Niu et al., Immunology 2011
:
Lipopolysaccharide induced
miR-1224 negatively
regulates tumour necrosis factor-a gene expression by modulating
Sp1
Xu et al., J Biol Chem 2011
:
miR-365 , a novel negative regulator of interleukin-6 gene expression, is cooperatively
regulated by
Sp1 and NF-kappaB
Zhang et al., Carcinogenesis 2011
(Pancreatic Neoplasms) :
miR-132 was transcribed by RNA polymerase II, and
Sp1 played a major role in
miR-132 transcription
Wang et al., Am J Pathol 2011
(Carcinoma, Squamous Cell...) :
Moreover,
SP1 was negatively
regulated by
miR-375 , and knockdown of SP1 by siRNA inhibited cell malignant behaviors
Liu et al., Mol Cancer Ther 2012
(Breast Neoplasms) :
Betulinic acid dependent repression of
Sp1 , Sp3, Sp4, and Sp-regulated genes was
due , in part, to induction of the Sp repressor ZBTB10 and downregulation of
microRNA-27a (miR-27a) , which constitutively inhibits ZBTB10 expression, and we show for the first time that the effects of betulinic acid on the miR-27a : ZBTB10-Sp transcription factor axis were cannabinoid 1 (CB1) and CB2 receptor dependent, thus identifying a new cellular target for this anticancer agent
Wang et al., J Pathol 2013
(Colorectal Neoplasms...) :
SP1 mediates the link between methylation of the tumour suppressor
miR-149 and outcome in colorectal cancer
Guo et al., Med Oncol 2013
(Neoplasm Invasiveness...) :
Moreover, we also showed that
Sp1 was negatively
regulated by
miR-22 at the posttranscriptional level, via a specific target site within the 3'UTR by luciferase reporter assay
Mao et al., Oncol Rep 2013
:
Overexpression of
miR-330 by transfection of a chemically synthesized miR-330 mimic
induced a reduction in expression levels of the
Sp1 protein, accompanied by significant suppression of cellular migration and invasion capability