◀ Back to TP53

IFI27 — TP53

Text-mined interactions from Literome

Pei et al., Clin Cancer Res 2004 (Multiple Myeloma) : These events were associated with nuclear factor kappaB inactivation, c-Jun NH ( 2 ) -terminal kinase activation, p53 induction , and caspase dependent cleavage of p21 ( CIP1 ), p27 ( KIP1 ), and Bcl-2, as well as Mcl-1, X-linked inhibitor of apoptosis, and cyclin D1 down-regulation
Lee et al., Head Neck 2004 (Carcinoma, Squamous Cell...) : Overexpression of p53 markedly downregulated the transcription of COX-2, but the overexpression of p27 did not affect COX-2 levels in HNSCC cell lines
Choi et al., J Nutr Biochem 2009 (Breast Neoplasms) : In an additional study, apigenin also increased the accumulation of p53 and further enhanced the level of p21 ( Cip1 ), with no change in p27 ( Kip1 )
Song et al., Mol Cancer Res 2008 : Expression of an IFN-inducible cellular senescence gene, IFI16 , is up-regulated by p53
Samba-Louaka et al., Infect Immun 2009 : Increases of p21 and p27 levels are independent of p53 transcriptional induction and result from protein stabilization through inhibition of the ubiquitin/proteasome degradation pathway
Ikari et al., J Cell Biochem 2011 : Together, lack of magnesium may increase p21 ( Cip1 ) and p27 ( Kip1 ) levels mediated by the decrease in ATP content and the activation of p53 , resulting in the suppression of cell cycle progression from G1 to S phase in NRK-52E cells