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TP53 — TTK
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Salvatore et al., Cancer Res 2007
(Carcinoma...) :
Adoptive overexpression of
p53 , p21 ( CIP1/WAF1 ), and E2F4
down-regulated transcription from the PLK1 and
TTK promoters in ATC cells, suggesting that these genes might be under the negative control of tumor suppressors of the p53 and pRB families
Huang et al., Mol Cell Biol 2009
(Polyploidy) :
Here we present evidence that stabilization and activation of
p53 by spindle disruption
requires the spindle checkpoint kinase
TTK/hMps1