Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
Complex of DVL2-DVL3-PRKCA-RHOA
→
WNT3A
(increases)
Evidence: PKCa, PCKb, and PKCmu were associated with both Dvl-2 (Figure 8A) and Dvl-3 (Figure 8B), suggesting that several PKCs are likely included in the Dvl/RhoA complex.
OpenBEL Selventa BEL large corpus:
PRKCA
→
WNT3A
(increases, WNT3A Activity)
Evidence: Having demonstrated activation of PKCa, PKCb, and PKCmu following Wnt treatmena
OpenBEL Selventa BEL large corpus:
PRKCA
→
WNT3A
(increases, WNT3A Translocation)
Evidence: Following Wnt-3a treatment, proteins were isolated from the respective cellular fractions and subjected to immunoblot analysis. Membrane fractions of both H929 and OPM-2 (Figure 5A-B) evidenced increases in PKCa, PKCb, and PKCmu, whereas no other isozymes were increased in this fraction (not shown) with the exception of PKCeta that only increased in OPM-2.