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RB1 — TCF12

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Dip Interaction: Complex of 18 proteins (anti tag coimmunoprecipitation) Hu et al., Proc Natl Acad Sci U S A 2009

Text-mined interactions from Literome

Staehling-Hampton et al., Genetics 1999 : The activity of the E2F transcription factor is regulated in part by pRB , the protein product of the retinoblastoma tumor suppressor gene
Osuga et al., Proc Natl Acad Sci U S A 2000 (Ischemic Attack, Transient...) : Deregulated levels of E2F1, a transcription factor regulated by pRb , are also observed
Zhu et al., Exp Cell Res 1997 (Breast Neoplasms...) : Cyclin D3 and CDK4 are likely the early targets of RA, followed by reduced pRB expression and phosphorylation, as well as by the inhibition of the E2F1 transcription factor which controls progression from G1 to S phase