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CASP6 — NR0B1
Text-mined interactions from Literome
Kwon et al., Life Sci 2007
:
We investigated
dextran sulfate sodium (DSS) induced IL-1 beta production and
caspase-1 activities in murine peritoneal macrophages ( pM phi ) ... IL-1 beta release and
caspase-1 activity
induced by
DSS were significantly inhibited by a MAPK kinase 1/2 inhibitor, a p38 MAPK inhibitor, and NAC, however, not by JNK1/2 or a protein kinase C inhibitor
Bauer et al., Gut 2010
(Colitis...) :
IL-1beta secretion was abrogated in macrophages lacking NLRP3, ASC or caspase-1, indicating that
DSS activates
caspase-1 via the NLRP3 inflammasome