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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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CASP7 — CSF2

Text-mined interactions from Literome

Watson et al., FEBS Lett 1999 : LPS, GM-CSF and increased glutathione stabilised the mitochondria and inhibited caspase 3
Ottonello et al., J Leukoc Biol 2002 (Granulomatous Disease, Chronic) : Accordingly, the spontaneous activity of caspase-3 was inhibited by GM-CSF , IL-6, and IL-15
Hsu et al., J Leukoc Biol 2002 : Annexin V staining and MTT assays reveal that PS-G is able to inhibit spontaneous and Fas induced neutrophil apoptosis, and this effect of PS-G is enhanced by the presence of zVAD ( a caspase inhibitor ) and GM-CSF
Zeigler et al., J Biol Chem 2003 : The caspase-3-selective inhibitor DEVD-fluoromethyl ketone reversed DNA fragmentation events, and the caspase-9 inhibitor LEHD-fluoromethyl ketone reversed caspase-3 activity in monocytes treated with PAPA or DEA NONOate in the presence of macrophage colony stimulating factor
Faderl et al., Blood 2003 (Acute Disease...) : Concurrently, GM-CSF stimulated expression of SOCS-2 and -3 and of procaspases 2 and 3 and induced caspase 3 activation, poly ( ADP [ adenosine 5'-diphosphate ] -ribose ) polymerase ( PARP ) cleavage, and apoptotic cell death ... The Janus kinase ( Jak ) -Stat inhibitor AG490 abrogated GM-CSF induced expression of procaspase 3 and activation of caspase 3
Murata-Ohsawa et al., Int J Mol Med 2004 (MAP Kinase Signaling System) : GM-CSF stimulation induced the phosphorylation of ERK1/2 and STAT5 and the cleavage of caspase-8 , which were not affected by Delta-1 incubation, either
Scheller et al., J Neural Transm Suppl 2006 : In previous studies we have reported that caspase inhibitors induce expression of various proinflammatory cytokines in CD95 stimulated primary T cells, such as TNF-alpha, IFN-gamma and GM-CSF
Yamashita et al., Blood 1999 : Granulocyte-macrophage colony stimulating factor inhibited TNF-alpha induced caspase activation and apoptosis, while reversing the diminution in superoxide release