◀ Back to GNG13
GCG — GNG13
Pathways - manually collected, often from reviews:
-
Reactome Reaction:
GNG13
→
GCG
(reaction)
Text-mined interactions from Literome
Wasserman et al., Am J Physiol 1989
:
In conclusion, in the dog, the exercise induced rise in
glucagon 1 ) controls approximately 65 % of the increase in Ra, 2 )
increases hepatic glycogenolysis and
GNG , and 3 ) enhances GNG by stimulating precursor extraction by the liver and precursor conversion to glucose within the liver
Cherrington et al., J Clin Invest 1978
(Diabetes Mellitus, Experimental...) :
It can be concluded that ( a ) the effect of relative hyperglucagonemia on GP is short lived ; ( b ) the waning of the effect of glucagon is attributable solely to a diminution of glycogenolysis because GNG remains stimulated ; ( c ) basal
glucagon markedly
enhances the
GNG stimulation apparent after induction of insulin deficiency ; and ( d ) basal glucagon worsens the hyperglycemia pursuant on the induction of insulin deficiency both by triggering an initial overproduction of glucose and by maintaining the basal production rate thereafter