Khatib et al., Cytokine 2002
:
Mechanism of inhibition of endothelin-1 stimulated proteoglycan and collagen synthesis in rat articular chondrocytes ... The aim of this study was to determine the effects of endothelin-1 (ET-1) on proteoglycan ( PG ) and collagen synthesis by rat articular chondrocytes ( RAC )
Little et al., J Cardiovasc Pharmacol 2010
:
Endothelin-1 stimulation of proteoglycan synthesis in vascular smooth muscle is mediated by endothelin receptor transactivation of the transforming growth factor- [ beta ] type I receptor ... Functionality of the interaction was addressed by studying endothelin-1 stimulated proteoglycan synthesis ... Endothelin-1 stimulated proteoglycan synthesis was partially inhibited ( 40 % ) by SB431542 and completely blocked by bosentan