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IL6 — MPG

Text-mined interactions from Literome

Tamion et al., Crit Care Med 2000 (Shock, Hemorrhagic) : MPG also reduced TNF-alpha and IL-6 mRNA expression ( as measured by reverse transcriptase-polymerase chain reaction ) assessed in peritoneal macrophages isolated from shock rats ... Finally, in vitro experiments showed that MPG also markedly reduced the mRNA expression and release of TNF-alpha and IL-6 in peritoneal macrophages isolated from normal rats and subjected to hypoxia and reoxygenation
Hmama et al., Clin Exp Immunol 1992 : Kp-MPG induced the synthesis of IL-1 beta, IL-6 and TNF-alpha with dose-responses and kinetics similar to those of Salmonella minnesota lipopolysaccharide ( Sm-Re-LPS )
Sironi et al., Int J Immunopharmacol 1990 : The present study was designed to investigate the effect of membrane proteoglycans (MPG) from Klebsiella pneumoniae on IL-6 production by human peripheral blood monocytes ... MPG induced hybridoma growth factor activity was blocked by anti-IL-6 antibodies ... Induction of IL-6 in mononuclear phagocytes may play a role in the immunomodulatory activity of MPG
Millet et al., Clin Exp Immunol 1987 : Conversely Kp MPG did not induce interleukin 2 production and did not trigger the proliferation of thymocytes but stimulated interleukin 1 production by adherent spleen cells ... It is concluded that Kp MPG is a T-independent polyclonal B cell activator and an inducer of interleukin 1 production