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CTNNB1 — RBX1
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Angers et al., Nat Cell Biol 2006
:
Considered with evidence that the distinct Cullin-1 based
SCF(beta-TrCP)complex regulates
beta-catenin stability, our data on the stability of Dishevelled demonstrates that two distinct ubiquitin ligase complexes regulate the Wnt-beta-catenin pathway
Megy et al., FEBS Lett 2006
(Neoplasms) :
Phosphorylation of
beta-Catenin at sites Ser33 and Ser37 on the DSGXXS motif is
required for the interaction of beta-Catenin with the ubiquitin ligase
SCF(beta-TrCP)