Gene interactions and pathways from curated databases and text-mining

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ADD1 — INS

Text-mined interactions from Literome

Foretz et al., Mol Cell Biol 1999 : We show here that the transcription of ADD1/SREBP-1c in primary cultures of hepatocytes is controlled positively by insulin and negatively by glucagon and cyclic AMP, establishing a link between this transcription factor and carbohydrate availability
Lacasa et al., J Biol Chem 2001 : Fatty acid synthase (FAS), a nutritionally regulated lipogenic enzyme, is transcriptionally controlled by ADD1/SREBP1c ( adipocyte determination and differentiation 1/sterol regulatory element binding protein 1c ), through insulin mediated stimulation of ADD1/SREBP1c expression