◀ Back to INS
DPP7 — INS
Text-mined interactions from Literome
Hollander et al., Postgrad Med 2010
(Cardiovascular Diseases...) :
By enhancing and prolonging incretin effects,
DPP-4 inhibitors
stimulate glucose dependent
insulin secretion and also reduce glucagon secretion
Wang et al., Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2013
:
In recent years, studies have revealed many possible mechanisms through which DPP-4 inhibitors regulate glycemia
: DPP-4 inhibitors may selectively reduce DPP-4 activity in the intestine, causing the increase of portal plasma GLP-1 level and thus
promoting the release of
insulin via nerve reflex ; also, they may decrease the cleavage product of GLP-1 and reduce the degradation of other bioactive peptides