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Text-mined interactions from Literome
Ban et al., Diabetes 2000
:
Furthermore, when transfected into rat primary cultured islets,
ATF-2 enhanced glucose induced
insulin promoter activity, whereas cAMP response element binding protein ( CREB ) repressed it
Zmuda et al., Mol Endocrinol 2010
(Diabetes Mellitus, Type 2) :
However,
ATF3 deficiency significantly
reduced serum
insulin levels in the KO mice without affecting insulin sensitivity, suggesting reduced beta-cell function in the KO mice