Gene interactions and pathways from curated databases and text-mining

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INS — TGM3

Text-mined interactions from Literome

Lindsay et al., Biosci Rep 1990 : Ca ( 2+ ) -Induced insulin release from electropermeabilised islets is inhibited by the transglutaminase inhibitors monodansylcadaverine, glycine methylester, methylamine and cystamine but not by the control compounds dimethyl monodansylcadaverine and sarcosine methylester which lack the primary amine group
Sener et al., Endocrinology 1985 : Role of transglutaminase in insulin release
Bungay et al., Biochem J 1986 : A role for transglutaminase in glucose stimulated insulin release from the pancreatic beta-cell
Nowak et al., Metabolism 1983 : Extrapancreatic action of sulfonylureas : hypoglycemic effects are not dependent on altered insulin binding or inhibition of transglutaminase ... Thus, the hypoglycemia caused by sulfonylurea administration could not be attributed to increases in insulin binding, inhibition of transglutaminase activity, or enhanced insulin levels
Driscoll et al., Pancreas 1997 (Insulinoma...) : To examine whether transglutaminase could mediate effects of retinoids on insulin secretion, we measured ( i ) transglutaminase activity in islets from rats deficient in vitamin A or repleted with retinol or retinoic acid, ( ii ) transglutaminase activity in RINm5F and INS-1 insulin secreting cells cultured in retinol or retinoic acid, ( iii ) mRNA for transglutaminase in RINm5F and INS-1 cells, and ( iv ) insulin secretion from INS-1 cells in response to retinoic acid