We have a suspicion that you are an automated web bot software, not a real user.
To keep our site fast for other users, we have slowed down this page.
The slowdown will gradually disappear.
If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu.
Also note that all data for hgGeneGraph can be obtained through our public MySQL server and
all our software source code is available and can be installed locally onto your own computer.
If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
JavaScript is disabled in your web browser
You must have JavaScript enabled in your web browser to use the Genome Browser
Gene interactions and pathways from curated databases and text-mining
◀ Back to HSPA1A
DNAJB1 — HSPA1A
Pathways - manually collected, often from reviews:
KEGG Protein processing in endoplasmic reticulum :
HSPA1A/HSPA1B/HSPA1L/HSPA2/HSPA6/HSPA8
→
DNAJA1/DNAJA2/DNAJB1/DNAJB12/DNAJB2/DNAJC5/DNAJC5B/DNAJC5G
(protein-protein, binding/association)
KEGG Protein processing in endoplasmic reticulum :
DNAJA1/DNAJA2/DNAJB1/DNAJB12/DNAJB2/DNAJC5/DNAJC5B/DNAJC5G
→
HSPA1A/HSPA1B/HSPA1L/HSPA2/HSPA6/HSPA8
(protein-protein, binding/association)
KEGG Influenza A :
DNAJB1
→
Complex of DNAJC3-HSPA1A-HSPA1B-HSPA1L-HSPA2-HSPA6-HSPA8
(protein-protein, inhibition)
Reactome Reaction :
DNAJB1
→
HSPA1A
(indirect_complex)
Reactome Reaction :
DNAJB1
→
HSPA1A
(reaction)
Sauve et al., Biochemistry 2001 , Westerheide et al., Science 2009 , Jamonnak et al., Bioorg Chem 2010 , Raynes et al., PloS one 2013
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
IRef Hprd Interaction :
Complex of DNAJB1-HSPA1A-TTC1-TTC1-DNAJB1-HSPA1A-HSPA1A-DNAJB1-TTC1
(in vivo)
Oh et al., Mol Cells 2003 *
IRef Hprd Interaction :
DNAJB1
—
HSPA1A
(in vivo)
Michels et al., J Biol Chem 1999 *
IRef Hprd Interaction :
DNAJB1
—
HSPA1A
(in vitro)
Michels et al., J Biol Chem 1999 *
IRef Intact Interaction :
Complex of 11 proteins
(association, tandem affinity purification)
Takai et al., Genes Dev 2010
IRef Intact Interaction :
Complex of 400 proteins
(association, cross-linking study)
Humphries et al., Science signaling 2009
IRef Intact Interaction :
Complex of 25 proteins
(association, anti bait coimmunoprecipitation)
Wang et al., Cell 2006
STRING interaction :
HSPA1A
—
DNAJB1
(interaction, mapped from kegg_pathways)
STRING interaction :
DNAJB1
—
HSPA1A
(interaction, mapped from kegg_pathways)