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IL10 — RABEPK

Text-mined interactions from Literome

Lenert et al., J Clin Immunol 2003 (Disease Models, Animal...) : Neutralizing anti-IL-10 antibodies almost completely restored PN IL-6 and IL-12p40 secretion to DBA-1 levels, whereas exogenous IL-10 inhibited in vitro IL-6 and IL-12p40 production in DBA-1 mice
Hoentjen et al., Blood 2005 : Chromatin immunoprecipitation demonstrated enhanced NF-kappaB ( cRel, RelA ) binding to the IL-12p40 promoter in IL-10 ( -/- ) but not WT BMDCs. Interestingly, LPS induced STAT3 phosphorylation in WT but not IL-10 ( -/- ) BMDCs, a process blocked by IL-10 receptor blocking antibody
Albright et al., Immunol Lett 2009 (Colitis) : Recombinant IL-10 suppressed and anti-IL-10 receptor antibody increased IFN-gamma, IL-17 and IL-12/IL-23 p40 production in bacterial lysate pulsed APC and plus CD4 ( + ) T cell co-cultures
Sarkar et al., Mol Cell Biol 2011 : To define the molecular mechanisms by which p40 ( AUF1 ) controls IL10 expression, we focused on the NF-?B pathway in search of AUF1 regulated targets
Güttsches et al., Innate Immun 2012 : However, when comparing LPS with lysate patterns, pro-inflammatory cytokine IL-12p40 was up-regulated by both LPS molecules and anti-inflammatory IL-10 by both lysates