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NR0B1 — RELA
Text-mined interactions from Literome
Bhattacharyya et al., Inflamm Bowel Dis 2009
:
DSS induced increases in phospho-IkappaBalpha, nuclear
NFkappaB ( p65 ), and IL-8 secretion in human colonic epithelial cells in tissue culture are attributable to a reactive oxygen species ( ROS ) -induced pathway of inflammation, and do not require TLR4, MyD88, or Bcl10, which are associated with the innate immune pathway of NFkappaB-IL-8 activation ... Data demonstrated that
DSS activates IkappaBalpha,
NFkappaB , and IL-8 through an ROS-Hsp27-IKKbeta mediated pathway, and not through an innate immune cascade
Youn et al., Nutr Cancer 2009
(Colitis...) :
Oral administration of resveratrol or piceatannol ( 10 mg/kg body weight each ) for 7 constitutive days attenuated the
DSS induced inflammatory injury, upregulation of iNOS expression, and activation of
NF-kappaB , STAT3, and ERK
Lee et al., Journal of inflammation (London, England) 2010
:
DSS and TNBS induced the protein expression of TLR-4 and
activated transcription factor
NF-kappaB