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CDC42 — MYCN
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Valentijn et al., Cancer Res 2005
(Neuroblastoma) :
N-myc also
inhibited Cdc42 functioning at the protein level
Joshi et al., Biochim Biophys Acta 2007
(Neuroblastoma) :
Poor invasiveness observed in SH-SY5Y, LA-N-5, and SMS-KCNR cells was associated with RA-induced neurite formation, Cdc42 activation and N-myc down regulation ; expression of constitutively active
Cdc42 down
regulated N-myc expression and reduced invasion in RA-resistant SK-N-BE ( 2 ) and IMR32 cells