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BMP7 — IL1B

Text-mined interactions from Literome

Gould et al., Kidney Int 2002 : BMP-7 represses the basal and TNF-alpha stimulated expression of the pro-inflammatory cytokines IL-6 and IL-1beta , the chemokines MCP-1 and IL-8, and the vasoconstrictor ET-2 in PTEC
Yoshida et al., Tohoku J Exp Med 2002 : Induction of osteogenic protein-1 expression by interleukin-1beta in cultured rabbit articular chondrocytes ... To elucidate the effects of interleukin-1beta (IL-1beta) on osteogenic protein-1 (OP-1) gene expression in a polylayer culture of rabbit articular chondrocytes, we measured rabbit OP-1 mRNA using quantitative TaqMan reverse transcriptase-polymerase chain reaction ( RT-PCR ) techniques ... Our results demonstrate that OP-1 expression is induced by IL-1beta and suggest that this expression, like that of HAS-2, may play a role as a protective mechanism against inflammatory cytokines
Elshaier et al., Arthritis Rheum 2009 (MAP Kinase Signaling System) : Effect of interleukin-1beta on osteogenic protein 1-induced signaling in adult human articular chondrocytes ... Two major receptor activated Smad (R-Smad) signaling pathways, bone morphogenetic protein ( BMP ) and MAPK, were examined in a model of interleukin-1beta (IL-1beta) induced cartilage degeneration to investigate the effect of IL-1beta on osteogenic protein 1 (OP-1) signaling in adult human articular chondrocytes ... The effect of IL-1beta on BMP receptors was studied by reverse transcription-polymerase chain reaction and flow cytometry